| NCAAF | 09/17 18:00 | 1 | Iowa Wesleyan v Finlandia Lions | W | 55-0 | |
| NCAAF | 09/10 18:00 | 1 | Westminster Blue Jays v Iowa Wesleyan | W | 6-41 | |
| NCAAF | 10/02 18:00 | 1 | Iowa Wesleyan v Crown Storm | W | 69-28 | |
| NCAAF | 09/11 18:00 | 1 | Iowa Wesleyan v Quincy | L | 27-59 | |
| NCAAF | 11/16 18:00 | 1 | Iowa Wesleyan v Northwestern Eagles | L | 6-42 | |
| NCAAF | 11/09 19:00 | 1 | Greenville Panthers v Iowa Wesleyan | L | 21-0 | |
| NCAAF | 11/02 17:00 | 1 | St Scholastica Saints v Iowa Wesleyan | L | 61-8 | |
| NCAAF | 10/26 18:00 | 1 | Iowa Wesleyan v Macmurray Highlanders | L | 12-21 | |
| NCAAF | 10/12 17:00 | 1 | Martin Luther Knights v Iowa Wesleyan | L | 51-6 | |
| NCAAF | 10/05 18:00 | 1 | Crown Storm v Iowa Wesleyan | L | 35-0 | |
| NCAAF | 09/28 18:00 | 1 | Iowa Wesleyan v Minnesota Morris Cougars | L | 21-28 | |
| NCAAF | 09/21 18:00 | 1 | Iowa Wesleyan v Westminster Blue Jays | L | 7-35 | |
| NCAAF | 09/14 18:00 | 1 | Knox Prairie Fire v Iowa Wesleyan | L | 44-0 | |
| NCAAF | 09/08 00:00 | 1 | Cornell Rams v Iowa Wesleyan | L | 33-6 | |
| NCAAF | 11/10 18:00 | 1 | Northwestern Eagles v Iowa Wesleyan | L | 28-0 | |
| NCAAF | 11/03 18:00 | 1 | Iowa Wesleyan v Greenville Panthers | L | 20-30 | |
| NCAAF | 10/27 17:00 | 1 | Iowa Wesleyan v St Scholastica Saints | L | 20-44 | |
| NCAAF | 10/20 18:00 | 1 | Macmurray Highlanders v Iowa Wesleyan | L | 20-13 | |
| NCAAF | 10/06 18:00 | 1 | Iowa Wesleyan v Martin Luther Knights | L | 21-28 | |
| NCAAF | 09/29 17:00 | 1 | Iowa Wesleyan v Crown Storm | W | 44-7 | |
| NCAAF | 09/22 17:00 | 1 | Minnesota Morris Cougars v Iowa Wesleyan | L | 13-7 | |
| NCAAF | 09/15 18:00 | 1 | Westminster Blue Jays v Iowa Wesleyan | L | 35-10 | |
| NCAAF | 09/02 00:00 | 1 | Iowa Wesleyan v Cornell Rams | L | 21-27 |